Symptomatic improvement of stiff-person syndrome during pregnancy

Takeaway

  • Clinical symptoms of stiff-person syndrome (SPS), a rare neuroimmunologic condition, appear to improve after the first trimester in pregnant women.

Why this matters

    Although SPS is more common in women, there is limited data in the effects of pregnancy on SPS. These findings could help clinicians looking to decrease the use of benzodiazepines toward the end of pregnancy to avoid neonatal dependence at delivery.

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