An evaluation of potential diagnostic and prognostic biomarkers in amyotrophic lateral sclerosis

Takeaway

  • Neurofilament light chain levels could be effective diagnostic and prognostic differential biomarkers in amyotrophic lateral sclerosis.

Why this matters?

  • Novel, more effective neurochemical biomarkers are needed to accurately predict diagnosis and prognosis in amyotrophic lateral sclerosis.

  • This unique integrated evaluation of a panel of neurochemical biomarkers reveals neurofilament light chain as a potential diagnostic and prognostic biomarker in differentiating amyotrophic lateral sclerosis from its mimic disorders.